Biostatistics and Medical Informatics
School of Medicine and Public Health

Dave’s Favorite Lectures

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DeMets 30-Year Conference 2012

Symposium celebrating 30 years at the University of Wisconsin

David L. DeMets, PhD

Max Halperin Professor of Biostatistics
Department of Biostatistics and Medical Informatics
School of Medicine and Public Health
University of Wisconsin-Madison

Thursday, May 31, 2012

Welcome:

  • Robert Golden, Dean School of Medicine and Public Health
  • Marvin Zelen, Lemuel Shattuck Research Professor of Statistical Science, Department of biostatistics, Harvard School of Public Health

Session 1:

  • Janet Wittes, History of the NHLBI Biostatistics Branch and Its Role in the Early Development of Clinical Trials
  • Lawrence Friedman: ITT and Anturane Trials
  • Curt Furberg: Challenges in Documenting Drug Safety
  • Nancy Geller, DLD’s Continued Influence at NIH
  • Day 1 Welcome and Session 1 Video (2:08:46) YouTube

Session 2:

  • Charles Hennekens: Aspirin in the Treatment and Prevention of Cardiovascular Disease: Past, Present, and Future
  • Robert Califf: The Clinical Trials Enterprise: Getting Reliable Answers More Efficiently
  • Marc Pfeffer: Safety Monitoring on Clinical Trials and the TREAT Trial
  • Session 2 Video (1:35:48) YouTube

Session 3:

  • Susan Ellenberg: AIDS DSMB and Its Impact
  • Frank Rockhold: IDMC Liability Concerns: Who Protects the Guardians?
  • George Williams: The Nocturnal Oxygent Therapy Trial (NOTT): Lessons of Continuing Value
  • Session 3 Video (1:31:36) YouTube

Session 4:

  • Anastasio “Butch” Tsiatis: Group Sequential Methods
  • K.K. Gordon Lan: Alpha Spending Functions and Design of Clinical Trials
  • Tom Fleming: Surrogate Endpoints
  • Session 4 Video (1:33:05) YouTube

Reception/Dinner

  • Jonas Ellenberg

Friday, June 1, 2012

Introductory Remarks

  • Paul DeLuca, Provost, University of Wisconsin
  • Philip Farrell, Professor Emeritus, UW Department of Pediatrics
  • Marc Drezner, Senior Associate Dean for Clinical and Translational Research; Director, Institute for Clinical and Translational Research
  • Day 2 Opening Remarks Video (40:36) YouTube

Session 5:

  • Charlie Casper: Running a Data Coordinating/Biostatistics Center
  • Joshua Chen: Testing Superiority at Interim Analyses in a Non-Inferiority Trial
  • Jose Pinheiro: Dose Finding Under Model Uncertainty: the MCPMod Approach
  • Peng “Roger” Qu: Overview of Drug Development and Biostatistics in China
  • David Reboussin: Monitoring Intervention X Subgroup Interactions, and a Simplified Approach to Analysis of Mediation
  • Michelle Roth-Cline: Pediatric Ethics at the FDA: The Crossroads of Ethics, Medicine, Statistics, and Law
  • Session 5 Video (1:37:23) YouTube

Session 6: Panel Discussion

  • Chair: KyungMann Kim
  • Panelists: DeJuran Richardson, Stephen Gange, Fred Yang, Xiaoyin “Frank” Fan, Zhengqing Li, Muhammad “Jalal” Jalaludding
  • Panel Discussion Video (56:49) YouTube

Closing Remarks

Agenda: DeMets_30th_Year_Celebration Conference (PDF)

DeMets ENAR 2015

2015_DeMets Presidential Invited Keynote_Speaker Bio (PDF)

2015_DLD_Presidential Talk titled “Big Data, Big Opportunities, Big Challenges” (PPT)

More Favorite Lectures

Neaton-DeMets DMC Video Lectures

Biostatisticians and Leadership

Statistics 998 – Statistics and Ethics in Research

Surrogates for Clinical Trials Outcomes

Statistics 741 Lecture: Survival Analysis Issues

Vanderbilt University Medical Center Discovery Lecture: Impact of the RCT on Medical Care Including the COVID-19 Era (2021)

Challenges in Clinical Trials: Some Old & Some New, Stanford University, Feb 2015 (PPT)