Sampene, Emmanuel

Emmanuel Sampene
Associate Scientist, Department of Biostatistics & Medical Informatics
Room & Building: 
230 WARF

sampene [at]

Education & Research: 

BA, Mathematics, Caldwell College, New Jersey, 2006

PhD, Biostatistics, University of Pittsburgh, 2013

Selected Publications

Sampene, E. & Wahed, A.S. "A relatively simple efficient estimator for relative risk in case-cohort studies" Journal of Statistical Research (2016), 48-50, No. 2, 37-55

Swick, A., Stein, A., Saha, S., McCulloch, T., Hartig, G., Ong, I, Sampene, E., Prabakaran, P., Liu, C., Kimple, R. "Defining the boundaries and expanding the utility of head and neck cancer patient derived xenografts" Journal of Oral Oncology (2016), 64 65-72

Benjamin, M., Chaddha, A., Sampene, E., Field, M., Rahko, P., "Long-term Outcomes for Patients with Atrial Fibrillation and a Rapid Ventricular Response: A Comparison of Those with Reduced Versus Preserved Ejection Fraction at Initial Hospitalization" Am J Cardiol. (2016), 118 1831-1835

Denney, J.M., Bird, C., Gendron-Fitzpatrick, A., Sampene, E., Bird, I.M., Shah, D.M. "Renin- Angiotensin System Transgenic MouseModel Recapitulates Pathophysiology Similar to Human Preeclamp- sia with Renal Injury that may be Mediated through VEGF" American Journal of Physiology-Renal Physiology 312(3), F445-F455 DOI:10.1152/ajprenal.00108.2016

Miranpuri, G.S., Meethal, S.V., Sampene, E., Chopra, A., Buttar, S., Nacht, C., Moreno, N., Pa- tel, K., Resnick, D.K. "Folic acid modulates MMP2 expression, alleviates neuropathic pain and improves functional recovery in spinal cord injured rats" Annals of Neurosciences (2017) 24(2) 74-81. DOI:1159/000475896.

Wolfe, B., Wiepz, G., Schotzko, M., Bondarenko, G., Durning, M., Simmons, H., Mejia, A., Faith, N., Sampene, E., Suresh, M., Kathariou, S., Czuprynski, C., Golos, T. "Acute fetal demise with first trimester maternal infection with listeria monocytogenes in a nonhuman primate model" mBio (2017) 8(1) e01938-16. DOI:10.1128/mbio.01938-16.

Swick, A.D, Prabakaran, P.J, Miller, M., Javaid, A., Fisher, M., Sampene, E., Ong, I.M., Lida, M., Wheeler, D.L., Nickel, K., Kimple, R.J. "Co-targeting mTORC and EGFR signaling as a potential therapeutics strategy in HNSCC" Molecular Cancer Therapeutics (2017) 16(7) 1257-1268. DOI:10.1158/1535-7163.

Prabakaran, P.J, Javaid, A., Swick, A.D, Werner, L.R., Nickel, K., Miller, M., Sampene, E., Hu, R., Ong, I.M., Bruce, J.Y., Hartig, G.K., Wieland, A.M., Canon, J., Harari, P.M., and Kimple, R.J. "Radiosensitization of adenoid cystic carcinoma with MDM2 inhibition" Cancer Clinical Research (2017), DOI:10.1158/1078-0432.CCR-17-0969.

Chuk, M., Chang, J., Theoret, M., Sampene, E., He, K., Weis, S. L., Helms, W. S., Jin, R., Li, H., Yu, J., Zhao, H., Zhao, L., Paciga, M., Schmiel, D., Rawat, R., Keegan, P., and Pazdur, R. "FDA Approval Summary: Accelerated Approval of Pembrolizumab for Advanced Refractory Melanoma" Cancer Clinical Research (2017). DOI:10.1158/1078.

Moran, P.M., Sampene, E., Oakes, S.G., Miranpuri, G.S., and Resnick, D.K. "Immediate Administration of COX Inhibitors in Spinal Cord Contusion Injury and a Current Review of COX Therapy" Medical Research and Innovations (2017) 1(5) 1-13

Wright, M., Sampene, E., & Safdar, N. "The Relationship Between Infection Prevention Staffing Levels, Certification, and Publicly Reported Hospital-Acquired Condition Scores" Infection Control & Hospital Epidemiology, 1-2. DOI:10.1017/ice.2017.187

Kapur, A., Beres, T., Rathi, K., Nayak, A.K., Felder, M., Gillette, A., Ericksen, S., Sampene, E., Skala, M., Barroilhet, L., Patanka, M. "Oxidative stress via inhibition of the mitochondrial electron transport and subsequent Nrf-2-mediated anti-oxidative response regulate the cytotoxic activity of plumbagin" Scientific Reports (2018) 81073. DOI:10.1038/s41598-018-19261-w.

Sadowski, E.A., Paroder, V., Lippmann, K.P., Robbins, J., Sampene, E. and Barroilhet, L. "Indeterminate adnexal cysts by ultrasound:prevalence and characteristics of ovarian cancer" Radiology (2018) 287(3) 1041-1049

Lewandowski, D., Pierce,D., Barnett, A.,Sampene, E., Safdar, N., Field, M., and Wright, J. "Impact of antibiotic prophylaxis on catheter associated UTI in patients undergoing AF ablations" Journal of Interventional Cardiac Electrophysiology (2018) 51(2), pp 183-187.

Pulia, M., Shah, M., Kern, M., Schwei, R., Sampene, E., Crnich, C.J. "Comparative Analysis of Antibiotic Prescribing Appropriateness for Long Term Care Facility Residents in Outpatient Settings" Journal of Antimicrobial Resistance and Infection Control (2018) 7(74) 1-8.

Barroilhet, L., O'Shea, A., McCool. K., Harrison, R., Sampene, E., and Connor, J. "Neoadjuvant chemotherapy is associated with more anemia and perioperative blood transfusions than primary debulking surgery in women with advanced stage ovarian cancer" Gynecologic Oncology (2018) 150(1) 19-22.

Kumar, N., Garg, N.D., Sampene, E., and Pandey, A. "Seasonal and Geographic Patterns in Seeking Cardiovascular Health Information on Google" Accepted by Mayo Clinic Proceedings (2018)

Atem F. D., Sampene, E. & Greene, T.J., "Improved Conditional Imputation In A Linear Regression With Randomly Censored Predictor" Statistical Methods in Medical Research (2017) DOI:10.1177


Methodology research in clinical trial designs, group sequential trials, survival analysis and longitudinal data analysis.