Gangnon, Ron

Ronald Gangnon
Professor, Department of Population Health Sciences and Department of Biostatistics & Medical Informatics
Room & Building: 
603 WARF

ronald [at]

Education & Research: 

PhD, 1998, University of Wisconsin-Madison

Research Interests
My statistical research interests include clustering, model selection, order-restricted inference, measurement reliability, survival analysis and interim monitoring. Recent research includes the development of a Bayesian approach for detecting and modeling spatial disease clustering; the development of a nonparametric method for assessing measurement reliability using bivariate isotonic regression; and the implementation of a randomization-based scheme for interim monitoring of multiple endpoints in clinical trials.

Selected Publications
Imesch PD, Bindley CD, Khademian Z, Ladd B, Gangnon RE, Albert DM and Wallow IH. Melanocytes and Iris Color: Electron Microscopic Findings. Archives of Ophthalmology 144(4): 443-447, 1996.

Davis MD, Fisher MR, Gangnon RE, Barton F, Aiello LM, Chew EY, Ferris FL 3rd, Knatterud GL. Risk factors for high-risk proliferative diabetic retinopathy and severe visual loss: Early Treatment Diabetic Retinopathy Study Report:18. Investigative Ophthalmology & Visual Science 39(2):233-52, 1998.

Perkins TW, Libby CM, Kaufman PL, Gangnon RE and Ladd W. Molteno Implant with Mitomycin C: Intermediate Term Results. Journal of Glaucoma. 7: 86-92, 1998.

Perkins TW, Gangnon RE, Ladd W, Kaufman PL and Heatley GA. Trabeculectomy with Mitomycin C: Intermediate Term Results. Journal of Glaucoma 7: 230-236, 1998.

Lewis R, Perkins TW, Gangnon RE, Kaufman PL and Heatley GA. The Rarity of Clinically Significant Rise in Intraocular Pressure after Laser Peripheral Iridotomy with Apraclonidine. Opthalmology 105:2256-2259, 1998.

Pratt L, Waschbusch L, Ladd W, Gangnon RE and Hendricks SK. Multiple v. Single Betamethasone Therapy: Neonatal and Maternal Effects. The Journal of Reproductive Medicine. 44(3): 257-264, 1999.

Peterson JA, Tian B, Bershadsky AD, Volberg T, Gangnon RE, Spector I, Geiger B, Kaufman PL, Latrunculin-A increases outflow facility in the monkey. Investigative Ophthalmology & Visual Science 40(5):931-41, 1999.

Ethier CR, Croft MA, Coloma FM, Gangnon RE, Ladd W, Kaufman PL. Enthacrynic and acid effects on inner wall pores in living monkeys. Investigative Ophthalmology & Visual Science 40(7):1382-91, 1999.

Gangnon RE and Clayton MK. Bayesian Detection and Modeling of Spatial Disease Clustering. Biometrics. 56(3): 922-935, 2000.

Gangnon RE and Clayton MK. A Weighted Average Likelihood Ratio Test for Spatial Disease Clustering. Statistics in Medicine. 20: 2977-2987, 2001.

Ip MS, Baker BJ, Duker JS, Reichel E, Baumal CR, Gangnon RE, and Puliafito CA. Anatomic Outcomes of Surgery for Idiopathic Macular Hole as Determined by Optical Coherence Tomography. Archives of Ophthalmology. 120: 29-35, 2002.

Safdar N, Said A, Gangnon RE and Maki D. Risk of Hemolytic Uremic Syndrome after Antibiotic Treatment of Escherichia coli O157:H7 Enteritis: A Meta-analysis. JAMA. 288(8): 996-1001, 2002.

Taglia DP, Perkins TW, Gangnon RE, Heatley GA and Kaufman PL. Comparison of the Ahmed Glaucoma Valve, the Krupin Eye Valve with Disk and the Double-Plate Molteno Implant. Journal of Glaucoma. 11(4): 347-353, 2002.

Gangnon RE and Clayton MK. Cluster Modelling for Disease Rate Mapping in Spatial Cluster Modelling, Denision D and Lawson A (eds), Chapman and Hall, 2002.

Gangnon RE and King W. Minimum Distance Estimation of the Distribution Functions of Stochastically Ordered Random Variables. Applied Statistics. 51(4): 485-492, 2002.

Binkley N, Kawahara-Baccus T, Krueger D, Li Z, Gangnon RE and Drezner MK. Are Wisconsin Physicians Knowledgeable about Male Osteoporosis? Wisconsin Medical Journal. 102(2): 51-57, 2003.

Gangnon RE and Kosorok MR. Weighted Log-rank Statistics and Sample Size Formula for Clustered Survival Data.Biometrika. To Appear.

Gangnon RE and Clayton MK. A Hierarchical Model for Spatial Clustering of Disease. Statistics in Medicine. To Appear.

Gangnon RE and Clayton MK. Likelihood-based Tests for Detecting Spatial Clustering of Disease. Environmetrics. Under Review.

Ip MS, Gottlieb JL, Kahana A, Scott IU, Altaweel MM, Blodi BA, Gangnon RE and Puliafito CA. Treatment of Macular Edema from Central Retinal vein Occlusion with Triamcinoline Acetonide. Archives of Ophthalmology. Under Review.

Albert DM, Gangnon RE, Zimbric ML, Fisher MR, Grossniklaus HE and Green WR. A Histopathologic Study of Iridectomy Specimens from Latanoprost and Non-Latanoprost Treated Patients. Archives of Ophthalmology. Under Review.

Hansen KE, Hilderbrand JP, Genovese MC, Cush JJ, Patel SR, Cooley DA, Cohen SB, Gangnon RE and Schiff MH. The Efficacy of Switching from Etanercept to Infliximab in Patients with Rheumatoid Arthritis. Journal of Rheumatology. Under Review.

Neaville WA, Tisler C, Anklam K, Gilbertson-White S, Hamilton R, Adler K, DaSilva DF, Roberg KA, Carlson-Dakes KT, Anderson E, Yoshihara D, Bhattacharya A, Gangnon RE, Mikus L, Rosenthal L, Gern JE and Lemanske RF. Developmental Cytokine Response Profiles and the Clinical and Immunologic Expression of Atopy in Infancy. Journal of Allery and Clinical Immunology. Under Review.

McMurray JE, Heilgers PJM, Shugerman R, Douglas J, Gangnon RE, Voss C and Linzer M. Part-time Medical Practice: Where Is It Now, and Where Is It Headed? American Journal of Medicine. Under Review.

Gern JE, Rock C, Li Z, Roberg KA, Carlson-Dakes KT, Adler K, Hamilton R, Anderson E, Gilbertson-White S, Tisler C, DaSilva D, Anklan K, Mikus LD, Rosenthal L, Gangnon RE and Lemanske RF. Effects of Pet Ownership on Patterns of Cytokine Secretion and Allergen Sensitization in Infancy. Journal of Allery and Clinical Immunology. Under Review.

Zakowski LJ, Cooney TG, Gangnon RE and Noel GL. General Internists Looking for Jobs: What are the Helpful Strategies? Journal of General Internal Medicine. Under Review.

Garry McCoy A, Smith EP, Atkinson ME, Baranski N, Kahl BS, Juckett M, Mitchell T, Gangnon R and Longo W. A Novel Preparative Regimen for Autologous Transplant in Non-Hodgkin's Lymphoma: Long-Term Experience with Etoposide and Thiotepa. Journal of Clinical Oncology. Under Review.

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Courses Taught

Spring 2000 - Statistics 351 (Introductory Non-Parametric Statistics)

Fall 2001 - Statistics 571 (Statistical Methods for Bioscience)

Spring 2003 - Statistics 572 (Statistical Methods for Bioscience II)


The development of a Bayesian approach for detecting and modeling spatial disease clustering. Model selection, order-restricted inference, measurement reliability, survival analysis and interim monitoring.